IMPACT OF CONCEIVE’S DAY OF A MENSTRUAL CYCLE ON CONGENITAL BIRTH DEFECT
RAJ NITESH KUMAR *
Primary Health Center, Arwal, Bihar, 804401, India.
*Author to whom correspondence should be addressed.
Abstract
The menstrual cycle is the regular natural change that occurs in the system, specifically the uterus and ovaries that makes pregnancy possible. The menstrual cycle consists of the follicular phase, ovulation, and the luteal phase. The median duration of a menstrual cycle is 28 days with most cycle lengths between 25 to 30 days. Ovulation takes place in med of cycle and Fertilization occurs after ovulation in fallopian tube. A sperm alive 4 days after discharged in female reproductive tract and ova survive 2 day after ovulation. So fertilization occurs almost at days 11th to 18th, rest days are called safe period. A disrupted cycle around the time of travelling is usually significant in relation to overall menstrual health. Climatic variations affects on woman menstrual cycles. In nearly 50% of cases the exact cause of congenital anomaly could not be identified, although there are some known risk factors which can be linked with the causation of malformation. Congenital anomalies can be caused by single gene defects, chromosomal disorders, multi-factorial inheritance and environmental factors. In a disrupted menstrual cycle, the day of ovulation varies and delay ovulation may be lead to congenital birth defect.
Keywords: Menstrual cycle, ovulation, biological clock, safe-period, environmental factors, congenital birth defect.
How to Cite
Downloads
References
Charan chatterjee CC. Human physiology. vol. ll Tenth Edition. 1995;4:195-283.
Padubidri VG, Shirish N Daftary. Shaw’s textbook of gynecology 13th Edition. 2004;38-47.
Kumar Pushkar, Singh AP. Life Cience. 2012;214-216.
Guyton C. Medical physiology 7th Edition. 2004;970-971.
Silverthorn DU. Human physiology: An integrated approach (6th ed.).Glenview, IL: Pearson Education. 2013;850–890.
Treloar AE. et al. Variation of the human menstrual cycle through reproductive life. Int J Fertil. 1967;12(1 Pt 2):77–126.
Davidson: Princiles and Practice of medicine 16th Edition. 1992;328-333.
WHO: Sixty-third world health assembly report on birth defect. 2010.
Amos Grunebaur: Lessens in Survival: All about Amos; 2019. [babymed.com]
Crow JF. The origins, patterns and implications of human spontaneous mutation. Nature Reviews Genetics. 2000;1(1):40-7.
Hoffmen JI, Kaplan S. The incidence of congenital heart disease. J Am coll Cardiol. 2002;39:1890-900.
Hoffmen JI, Kaplan S. Liberthson RR. Prevalence of congenital heart disease. Am heart J. 2004;147:425-39.